[HTML][HTML] The effect of a dual or a triple antithrombotic therapy with apixaban on thrombus formation in vivo and in an ex vivo perfusion chamber model: an open-label …
S Weisshaar, B Litschauer, S Bucher, M Riesenhuber… - Medicine, 2016 - journals.lww.com
Background: There is a need to optimize pharmacological treatment in patients with acute
coronary syndrome and concomitant atrial fibrillation, in particular with newer antithrombotic
medicines. We have therefore studied if dual or triple combination of antithrombotic agents
exert similar effects on coagulation activation in an in vivo model in the skin
microvasculature and in an ex vivo perfusion chamber. Methods and Results: Shed blood
platelet activation (β-thromboglobulin [β-TG]), thrombin generation (thrombin-antithrombin …
coronary syndrome and concomitant atrial fibrillation, in particular with newer antithrombotic
medicines. We have therefore studied if dual or triple combination of antithrombotic agents
exert similar effects on coagulation activation in an in vivo model in the skin
microvasculature and in an ex vivo perfusion chamber. Methods and Results: Shed blood
platelet activation (β-thromboglobulin [β-TG]), thrombin generation (thrombin-antithrombin …
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